Effects of niacin on glucose levels, coronary stenosis progression, and clinical events in subjects with normal baseline glucose levels (<100 a="" analysis="" and="" armed="" atherosclerosis="" by="" carotid="" combined="" composition="" dl="" during="" familial="" forces="" hdl-atherosclerosis="" lipid-lowering="" mg="" mri="" of="" plaque="" regression="" study.="" study="" the="" treatment="">
Phan BA, Muñoz L, Shadzi P, Isquith D, Triller M, Brown BG, Zhao XQ.

SourceDivision of Cardiology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA. bphan@lumc.edu



Abstract

Although the effect of niacin on the glucose levels in subjects with diabetes mellitus has been investigated, niacin's effects on the glucose levels and atherosclerosis in subjects with normal glucose levels have not been well established. We examined the effect of niacin on the glucose levels, coronary stenosis progression using quantitative coronary angiography, and clinical events in 407 subjects who had a baseline glucose level <100 0.3="" 12="" 17.9="" 19.7="" 21="" 29="" 2="" 3="" 4.05="" 4.8="" 85.2="" 85.6="" 9.5="" 9.6="" 90="" 95.5="" a="" active="" although="" an="" and="" armed="" associated="" atherosclerosis="" baseline="" be="" between="" blood="" both="" but="" by="" cardiovascular="" carotid="" change="" compared="" composition="" conclusion="" coronary="" developed="" developing="" diabetes="" did="" differ="" dl="" during="" enrolled="" events.="" events="" familial="" fasting="" for="" forces="" frequency="" from="" glucose="" groups="" had="" hdl-atherosclerosis="" however="" impaired="" in="" incidence="" incident="" increase="" increased="" larger="" less="" levels="" likely="" lipid-lowering="" major="" mean="" mellitus="" mg="" more="" mri="" new-onset="" niacin-treated="" niacin="" normal="" not.="" not="" observed="" of="" or="" overall="" p="0.001)." plaque="" progression="" reduced="" regression="" risk="" significantly="" stenosis="" study="" subjects="" taking="" testing="" than="" the="" therapy.="" those="" to="" treated="" treatment="" untreated="" use="" vs="" was="" were="" who="" with="" within="" without="" years.="" years="">