MSM has been shown to break down the calcification that is frequently associated with chronic inflammation. In your arteries, it's called plaque, which leads to heart disease. These plaques are the root cause of inflammation.
"MSM helps dissolve these calcified deposits, turning it into calcium sulfate and making it soluble so your body can excrete it," David explains.Keep in mind that there may be side effects because MSM can detoxify you, and that may initially aggravate any condition you have. So increase dosage slowly to allow your body to adjust.
"The dosage of MSM has to be, in the beginning, maybe 2,500 mg per day. But really, you need to get up to 5,000 mg or 7,500 mg, and allow it to work over a period of months.
But don't ever want to start anything at a very high dosage. Move into it gently.
I have a good friend of mine who is now taking 30,000 mg of MSM for his rheumatoid arthritis, and that is the dosage he needs in order to feel complete relief of his pain."
It's also important to note that if you're allergic to sulfa drugs, you may also have trouble with MSM because it is a type of sulfur.
MSM is not a drug however. It is a natural compound that exists in all trees and many plants. MSM is highly concentrated in aloe vera, for example, so you can also use natural aloe vera products that contain MSM in its natural form.
As with most supplements, quality is a concern when it comes to MSM as well. David recommends using wood pulp or tree-derived MSM.
From: http://articles.mercola.com/sites/articles/archive/2010/07/17/superfood-expert-david-wolfe-shares-latest-insights-on-how-to-stay-healthy.aspx